Version 5.6, part of Release 2017a, includes the following enhancements:

  • Parameter Estimation: Estimate parameters using scatter search global optimization​
  • SimFunction with Variants: Specify parameters for simulation​ using variants
  • SBML Support: Load SBML models with function definitions, and models that use reaction IDs to reference reaction rates in mathematical expressions
  • Performance: Provide faster compilation of SimBiology models and faster simulation of models with large numbers of dosing events
  • Diagram View: Navigate between clone blocks, change reactions graphically, and generate variants from estimation and simulation results

See the Release Notes for details.

Version 5.5, part of Release 2016b, includes the following enhancements:

  • Noncompartmental Analysis: Handle sparse sampling in addition to serial sampling​
  • Diagram View: Configure block properties in place with graphical context menus
  • Diagram View: Access model information directly from the graphical view
  • Model Usages: Determine model component usage from the command line using findUnusedComponents and findUsages function

See the Release Notes for details.

Version 5.4, part of Release 2016a, includes the following enhancements:

  • Progress Plot for Fitting: Visualize parameter estimation progress in real time for both desktop and cluster simulations
  • Model Selection Information: Report parameter estimation quality measures (log-likelihood, AIC, BIC) consistently across all estimation algorithms, allowing direct comparisons between model parameterizations
  • Steady States: Compute model steady states using the sbiosteadystate function, for example to equilibrate a model prior to dosing
  • SBML Support: Load and save the most recent SBML file format (level 3 version 1)
  • Model Examples: Open SimBiology model examples hosted on the MATLAB Central File Exchange from within the SimBiology desktop
  • Block Property Editor: Display and edit block properties with a single click

See the Release Notes for details.

Version 5.3, part of Release 2015b, includes the following enhancements:

  • Application builder for model distribution and simulation​
  • Equations view of models
  • Viewing and editing reaction rates in the diagram view
  • Bioavailability example

See the Release Notes for details.

Version 5.2, part of Release 2015a, includes the following enhancements:

  • Graphical representation of all modeling constructs
  • High-accuracy parameter sensitivities enabling more robust parameter optimization
  • Response-specific error models
  • Sensitivity analysis using the SimFunction object

See the Release Notes for details.