How do you calculate the volume of tumor from a series of MRI slices contaning tumor

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Hie, i am a PG student working on a project detection of tumor from a sequence of MRI slices. After detecting the tumor from the slices, i calculate the volume of tumor. can any one help me out with the code for calculating the volume. i have this code for calculating the volume could u help me understand this code. i didnt understand what does "level" mean.
function [tumorvolume,flag] = volumetumor(handles)
% % % handles % % % pause
delxx = handles.delxx;
delyy = handles.delyy;
delzz = handles.delzz;
imagedata = handles.onlytumor;
[nx,ny,nz] = size(imagedata);
level = 3;
tumorvolume = 0.0;
%%imagedata(:,:,1)
for k=1:nz
BW =(imagedata(:,:,k)>level);
total = bwarea(BW);
tumorvolume =tumorvolume+total*delxx*delyy*delzz;
end
tumorvolume; flag =1;

Accepted Answer

David Sanchez
David Sanchez on 25 Aug 2014
You have to know the scale of the images.
Once you know the scale (equivalence between pixel-size and mm, for example), you just measure the length and width of the tumor within each slice.
Add up the product of length*width from each slice.
Finally, the volume of the tumor will be the previous summation times the distance between each slice.
Volume = slice_distance*(sum(length*width));
  1 Comment
Sayali Lopez
Sayali Lopez on 25 Aug 2014
Edited: Sayali Lopez on 25 Aug 2014
Thanks a lot. This will surely help me. i have this code for calculating the volume could u help me understand this code. i didnt understand what does "level" mean.
function [tumorvolume,flag] = volumetumor(handles)
% % % handles % % % pause
delxx = handles.delxx;
delyy = handles.delyy;
delzz = handles.delzz;
imagedata = handles.onlytumor;
[nx,ny,nz] = size(imagedata);
level = 3;
tumorvolume = 0.0;
%%imagedata(:,:,1)
for k=1:nz
BW =(imagedata(:,:,k)>level);
total = bwarea(BW);
tumorvolume =tumorvolume+total*delxx*delyy*delzz;
end
tumorvolume; flag =1;

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