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In Simbiology, should the categorical variables be assigned as group variable or covariate in the dataset?

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I am using Simbiology for population pharmacokinetic model development. I use non-linear mixed effect modelling approach. I have a doubt in the intial assignment of data type in the dataset.
Suppose I have age and gender in the dataset. Clearly, I will assign age as covariate. Now gender is also a covariate. But there is a option in the dataset type which is group variable.
Now I am confused on whether I should assign gender as covariate or group variable.?
I am attaching a screenshot for the reference.


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Accepted Answer

Praveen Kumar M
Praveen Kumar M on 17 Jun 2019
Oh. That's a clear answer. I have a logical query. Among the covariate, one is a categorical variable (gender) and another is a continuous variable (age). How do I incorporate this information in the dataset / modelling?


Jeremy Huard
Jeremy Huard on 17 Jun 2019
It is not necessary to define it as categorical. But covariates require numerical data in SimBiology. In your case, since you have a binary covariate, you could set gender to 1 for female, 0 for male.

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More Answers (1)

Jeremy Huard
Jeremy Huard on 17 Jun 2019
Group variable defines an index for a subject/experiment. In your dataset, ID is a group variable. Gender and age can be both covariates.


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