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Why is performance on establishing a matfile object poor?

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Hi everybody,
I need a bit insights about matfile objects.
So the background is, I have a matfile containing several tall arrays (386 files) (matfile has a size of about 4.6 MB).
I use
data = matfile('MEA.mat');
to establish a matfile object on the MEA.mat file. It takes about 10 minutes.
So I wonder why it takes such a long time. Or is it long at all? I wonder how MATLAB proceeds on establishing such an object, and where is the bottleneck.
Thank you a lot for helping hints and information!
Eva

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