If you want to set initial condition targets for block variables, then you need to ensure that the "start from steady state" option is turned off. This is because when "start from steady state" is used, the solver does not necessarily use the initial condition targets you set for the variables and tries to find a steady state initial condition solution.
In general, if you have selected the Start simulation from steady state check box in the Solver block dialog box, the solver attempts to find the steady state (when the system variables are no longer changing with time). If the steady-state solve succeeds, the state found is some steady state (within tolerance), but not necessarily the state expected from the given initial conditions. In other words, if simulation starts from steady state, even the high-priority variable targets might no longer be satisfied at the start of simulation. However, if the model has more than one steady state, the variable targets you specify can affect which steady-state solution is selected by the solver.
If you want to get more information about this topic, the following links to our documentation may be of interest to you: Block-Level Variable Initialization and How Simscape Simulation Works
