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Automating Parameter Identifiability Analysis in SimBiology
Is it possible to develop a MATLAB Live Script that automates a series of SimBiology model fits to obtain likelihood profiles? The goal is to fit a kinetic model to experimental data while systematically fixing the value of one kinetic constant (e.g., k1) and leaving the others unrestricted.
The script would perform the following:
Use a pre-configured SimBiology project where the best fit to the experimental data has already been established (including dependent/independent variables, covariates, the error model, and optimization settings).
Iterate over a defined sequence of fixed values for a chosen parameter.
For each fixed value, run the estimation to optimize the remaining parameters.
Record the resulting Sum of Squared Errors (SSE) for each run.
The final output would be a likelihood profile—a plot of SSE versus the fixed parameter value (e.g., k1)—to assess the practical identifiability of each model parameter.
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For some time now, this has been bugging me - so I thought to gather some more feedback/information/opinions on this.
What would you classify Recursion? As a loop or as a vectorized section of code?
For context, this query occured to me while creating Cody problems involving strict (so to speak) vectorization - (Everyone is more than welcome to check my recent Cody questions).
To make problems interesting and/or difficult, I (and other posters) ban functions and functionalities - such as for loops, while loops, if-else statements, arrayfun() and the rest of the fun() family functions. However, some of the solutions including the reference solution I came up with for my latest problem, contained recursion.
I am rather divided on how to categorize it. What do you think?
For the www, uk, and in domains,a generative search answer is available for Help Center searches. Please let us know if you get good or bad results for your searches. Some have pointed out that it is not available in non-english domains. You can switch your country setting to try it out. You can also ask questions in different languages and ask for the response in a different language. I get better results when I ask more specific queries. How is it working for you?
Hello MATLAB Central community,
My name is Yann. And I love MATLAB. I also love Python ... 🐍 (I know, not the place for that).
I recently decided to go down the rabbit hole of AI. So I started benchmarking deep learning frameworks on basic examples. Here is a recording of my experiment:
Happy to engage in the debate. What do you think?
Hi,
I have some problem, I want to upload my data that sample rate at 500HZ, every sevral seconds.
My data include 12 bytes, and it measure 500HZ, for example for 15 seconds I coolect 15*500*12 = 84KB.
Can I upload this data to ThingSpeak? It is possible to use with Free acount (I am student and this is my project)
How can help me..
Large Language Models (LLMs) with MATLAB was updated again today to support the newly released OpenAI models GPT-5, GPT-5 mini, GPT-5 nano, GPT-5 chat, o3, and o4-mini. When you create an openAIChat object, set the ModelName name-value argument to "gpt-5", "gpt-5-mini", "gpt-5-nano", "gpt-5-chat-latest", "o4-mini", or "o3".
This is version 4.4.0 of this free MATLAB add-on that lets you interact with LLMs on MATLAB. The release notes are at Release v4.4.0: Support for GPT-5, o3, o4-mini · matlab-deep-learning/llms-with-matlab
Hey cody fellows :-) !
I recently created two problem groups, but as you can see I struggle to set their cover images :
What is weird given :
- I already did it successfully twice in the past for my previous groups ;
- If you take one problem specifically, Problem 60984. Mesh the icosahedron for instance, you can normally see the icon of the cover image in the top right hand corner, can't you ?
- I always manage to set cover images to my contributions (mostly in the filexchange).
I already tried several image formats, included .png 4/3 ratio, but still the cover images don't set.
Could you please help me to correctly set my cover images ?
Thank you.
Nicolas
Is there a hardware support package available for the MP series?
I'm facing an issue where my Thinkspeak graph is not displaying, even though I'm using exactly the same code as my friend. The code works perfectly in their Thinkspeak account, but not on mine. I've checked the API keys, channel settings, and data formats, but everything seems similar. Has anyone else faced this problem, or do you have tips on what to check next? Suggestions are welcome!
Hi!
I'm having trouble sending data to a channel using MQTT. I'm using a program that was working perfectly until just a few days ago, but after making some minor changes yesterday, it stopped working. I’ve also tested it manually using the MQTTX client. If I send data using CURL and GET, it works fine.
It’s a bit strange...
Thankfully,
Ernesto.
Is it possible to create a Simulink model that is independent of specific microcontrollers?
For example, in the model, the STM32 block is used for CAN transmission. But if I want to deploy the same model to an Arduino, I have to replace the STM32 block with an Arduino-compatible one.
So, is it possible to create a custom block or abstraction that works across multiple microcontrollers like STM32, PIC32, and Arduino without changing the hardware-specific block each time?
