SimBiology model for PK/PD of antibacterial drugs

SimBiology model for PK/PD of antibacterial drugs

SimBiology model characterizing the pharmacokinetic/pharmacodynamic (PK/PD) relationship of antimicrobial agents as described in the article, “Semi-mechanistic Model for Assessment of Activity of Antibacterial Agents from Time-Kill Curve Experiments” by Nielsen et al (see ref. in below)

Reference:

[1] Nielsen, E. I., A. Viberg, E. Lowdin, O. Cars, M. O. Karlsson, and M. Sandstrom (2007) Semimechanistic pharmacokinetic/pharmacodynamic model for assessment of activity of antibacterial agents from time-kill curve experiments. Antimicrobial Agents and Chemotherapy. 51:128-136.