Motion Estimation between Blocks from Two Images

I have two frames from a video divided into 16x16 blocks and I need to find the most similar area (Frame 2) to a randomly selected block in Frame1 using Motion Estimation.

Answer 1

[Matt J]

I imagine you would use imregtform to do the motion estimation. Once you have the motion tform, you would apply it to the centroid of the given block in Frame 1 and see where it moves to in Frame 2.