MathWorks - Mobile View
  • Sign In to Your MathWorks AccountSe connecter
  • Access your MathWorks Account
    • Mon compte
    • Mon profil
    • Mes licences
    • Se déconnecter
  • Produits
  • Solutions
  • Le monde académique
  • Support
  • Communauté
  • Événements
  • Obtenir MATLAB
MathWorks
  • Produits
  • Solutions
  • Le monde académique
  • Support
  • Communauté
  • Événements
  • Obtenir MATLAB
  • Sign In to Your MathWorks AccountSe connecter
  • Access your MathWorks Account
    • Mon compte
    • Mon profil
    • Mes licences
    • Se déconnecter

Vidéos et webinars

  • MathWorks
  • Vidéos
  • Vidéos
  • Recherche
  • Vidéos
  • Recherche
  • Contacter un commercial
  • Version d'essai
  Register to watch video
  • Description
  • Related Resources

Using SimBiology for Mechanism-Based PK/PD Modeling in Preclinical & Discovery

Asawari Samant, MathWorks

Drug developers are moving towards mechanism-based drug discovery, using mechanistic or semi-mechanistic models of drug action and efficiency to extend traditional PK modeling techniques.  These mechanism-based models are more suitable for prediction and extrapolation than pure empirical approaches.  In this webinar, you learn how to use SimBiology and MATLAB to implement mechanism-based PK/PD modeling workflows.

Using a modeling and simulation case-study from literature, we demonstrate:

• Building mechanism-based PK/PD models using an interactive block-diagram editor
• Estimating parameters by fitting experimental data
• Simulating different dosing strategies
• Exploring system dynamics using parameter sweeps & sensitivity analysis
• Automating and customizing analyses using MATLAB

We also highlight new features in SimBiology 2012a including:

• Simulation Viewer – a interactive visualization tool for model exploration
• Weighted fitting
• Simultaneously fitting data from multiple dose levels

Recorded: 26 Mar 2012

Related Products

  • SimBiology

Feedback

Featured Product

SimBiology

  • Request Trial
  • Get Pricing

Up Next:

46:14
Preclinical PK/PD modeling with SimBiology

Related Videos:

46:51
Using Systems Pharmacology Modeling Approaches to Guide...
2:45
Accelerating Drug Discovery and Development with SimBiology
37:40
Physiologically-based Modeling of Oral Drug Absorption with...
52:52
Population Pharmacokinetic Modeling Using Nonlinear...

View more related videos

MathWorks - Domain Selector

Select a Web Site

Choose a web site to get translated content where available and see local events and offers. Based on your location, we recommend that you select: .

Select web site

You can also select a web site from the following list:

How to Get Best Site Performance

Select the China site (in Chinese or English) for best site performance. Other MathWorks country sites are not optimized for visits from your location.

Americas

  • América Latina (Español)
  • Canada (English)
  • United States (English)

Europe

  • Belgium (English)
  • Denmark (English)
  • Deutschland (Deutsch)
  • España (Español)
  • Finland (English)
  • France (Français)
  • Ireland (English)
  • Italia (Italiano)
  • Luxembourg (English)
  • Netherlands (English)
  • Norway (English)
  • Österreich (Deutsch)
  • Portugal (English)
  • Sweden (English)
  • Switzerland
    • Deutsch
    • English
    • Français
  • United Kingdom (English)

Asia Pacific

  • Australia (English)
  • India (English)
  • New Zealand (English)
  • 中国
    • 简体中文Chinese
    • English
  • 日本Japanese (日本語)
  • 한국Korean (한국어)

Contact your local office

  • Contacter un commercial
  • Version d'essai

Découvrir les produits

  • MATLAB
  • Simulink
  • Version étudiante
  • Support Hardware
  • File Exchange

Essayer ou Acheter

  • Téléchargements
  • Version d'essai
  • Contacter un commercial
  • Tarifs et licences
  • Comment acheter

Se Former

  • Documentation
  • Tutoriels
  • Exemples
  • Vidéos et webinars
  • Formation

Obtenir de l'aide

  • Aide à l'installation
  • Forum MATLAB
  • Services de consulting
  • Gestion Licences
  • Contacter le support technique

La société

  • Offres d'emploi
  • Actualités
  • Social Mission
  • Contacter un commercial
  • La société

MathWorks

Accelerating the pace of engineering and science

MathWorks est le leader mondial des logiciels de calcul mathématique pour les ingénieurs et les scientifiques.

Découvrir…

  • Select a Web Site United States
  • Brevets
  • Marques déposées
  • Charte de confidentialité
  • Lutte anti-piratage
  • État des applications

© 1994-2021 The MathWorks, Inc.

  • Facebook
  • Twitter
  • Instagram
  • YouTube
  • LinkedIn
  • RSS

Rejoignez la conversation

This website uses cookies to improve your user experience, personalize content and ads, and analyze website traffic.  By continuing to use this website, you consent to our use of cookies.  Please see our Privacy Policy to learn more about cookies and how to change your settings.